Immune research
Thymosin α1
Published reviews describe a peptide produced naturally by the thymus that modulates the maturation of T cells and the function of dendritic cells, largely through Toll-like receptor signalling.
What PubMed contains
Each figure links to the query that produced it. Where a count is zero, the published evidence of that kind was absent from the index at the retrieval date — a fact about the literature, not a judgement of ours.
Selected literature
Published work on Thymosin α1
Thymosin alpha-1
ReviewAncell CD et al. 2001American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System PharmacistsPMID 11381492
Aging and Thymosin Alpha-1
ReviewSimonova MA et al. 2025International journal of molecular sciencesPMID 41373628
Thymosin alpha 1: A comprehensive review of the literature
ReviewDominari A et al. 2020World journal of virologyPMID 33362999
Thymosin alpha-1 treatment in chronic hepatitis B
StudyWu X et al. 2015Expert opinion on biological therapyPMID 25640173
Thymosin alpha 1 treatment for patients with sepsis
ReviewPei F et al. 2018Expert opinion on biological therapyPMID 30063866
Thymosin α-1 in cancer therapy: Immunoregulation and potential applications
StudyWei Y et al. 2023International immunopharmacologyPMID 36812669
Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis
StudyWei YT et al. 2022Cancer researchPMID 35364609
Clinical applications of thymosin alpha-1
ReviewGoldstein AL 1994Cancer investigationPMID 7922712
Phenotypic drug discovery: a case for thymosin alpha-1
ReviewGaraci E et al. 2024Frontiers in medicinePMID 38903817
Serum thymosin alpha 1 levels in normal and pathological conditions
ReviewPica F et al. 2018Expert opinion on biological therapyPMID 30063864
Bioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and Activity
StudyArmirotti A et al. 2019Scientific reportsPMID 31311979
Thymosin Alpha 1 Plus Routine Treatment for the Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis
Meta-analysisCao A et al. 2024Journal of the College of Physicians and Surgeons--Pakistan : JCPSPPMID 39648386
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This page is a bibliographic reference for research professionals. It is educational only, it is not medical, clinical, or legal advice, and it is not a recommendation to use any compound. Peptide research is an evolving field: counts and conclusions change as new work is published. Readers are responsible for evaluating the primary literature themselves and for consulting qualified professionals in their own jurisdiction.