Tissue repair research
KPV
The literature describes KPV as the C-terminal tripeptide — a short fragment from the tail end — of α-melanocyte-stimulating hormone, and reports anti-inflammatory activity in laboratory models.
What PubMed contains
Each figure links to the query that produced it. Where a count is zero, the published evidence of that kind was absent from the index at the retrieval date — a fact about the literature, not a judgement of ours.
Selected literature
Published work on KPV
Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway
StudySung J et al. 2025Tissue & cellPMID 40073467
Transdermal Iontophoretic Delivery of Lysine-Proline-Valine (KPV) Peptide Across Microporated Human Skin
StudyPawar K et al. 2017Journal of pharmaceutical sciencesPMID 28343991
Stability-indicating HPLC assay for lysine-proline-valine (KPV) in aqueous solutions and skin homogenates
StudyPawar KR et al. 2015Biomedical chromatography : BMCPMID 25298219
NLRP3 autophagic degradation disruption in melanocytes contributes to vitiligo development
StudyZeng K et al. 2026Cell death and differentiationPMID 40935835
Lysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells
StudyLee JY et al. 2026CytotechnologyPMID 42064835
KPV and RAPA Self-Assembled into Carrier-Free Nanodrugs for Vascular Calcification Therapy
StudyZhang L et al. 2024Advanced healthcare materialsPMID 39252648
Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis
StudyXiao B et al. 2017Molecular therapy : the journal of the American Society of Gene TherapyPMID 28143741
Biomimetic Melanosomes Promote Orientation-Selective Delivery and Melanocyte Pigmentation in the H(2)O(2)-Induced Vitiligo Mouse Model
StudySun MC et al. 2021ACS nanoPMID 34662120
Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model
StudyViennois E et al. 2016Cellular and molecular gastroenterology and hepatologyPMID 27458604
Downregulation of glucocorticoid receptors of liver cytosols and the role of the inflammatory cytokines in pathological stress in scalded rats
StudyLiu DH et al. 2002Burns : journal of the International Society for Burn InjuriesPMID 12052369
Molecular and neuronal mechanisms for amino acid taste perception in the Drosophila labellum
StudyAryal B et al. 2022Current biology : CBPMID 35176225
A PepT1 mediated medicinal nano-system for targeted delivery of cyclosporine A to alleviate acute severe ulcerative colitis
StudyWu Y et al. 2019Biomaterials sciencePMID 31408067
Research areas
Where this sits in the field
Related topics
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Provided for navigation. The literature above concerns a compound class as the published record describes it; it is not a representation about any product we sell, and no listing below has been evaluated against the research on this page.
This page is a bibliographic reference for research professionals. It is educational only, it is not medical, clinical, or legal advice, and it is not a recommendation to use any compound. Peptide research is an evolving field: counts and conclusions change as new work is published. Readers are responsible for evaluating the primary literature themselves and for consulting qualified professionals in their own jurisdiction.