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Longevity FAQ
6 questions chosen because they are the ones where mechanism runs furthest ahead of human outcome. Each opens with the verdict in one sentence — the answer is on the page before you click anything.
Where the honest answer is “in mice, and not yet in people”, it says that rather than implying more. Every citation resolves to a record in this section’s own corpus of 112 papers.
Epigenetic clocks read DNA methylation at a set of sites and return an age estimate, and the better ones predict population-level outcomes well — GrimAge in particular outperforms earlier clocks at predicting age-related disease and mortality across cohorts.
The problem is the jump from a cohort to you. A clock trained to predict average outcomes across thousands of people can be strongly predictive in aggregate while being noisy for one individual, and different clocks disagree with each other on the same sample. A review in this corpus sets out those measurement challenges directly, and it is filed as contesting the confident reading.
An expert consensus statement on ageing biomarkers reaches a similarly careful position: these are tools for evaluating interventions in studies, not yet a readout for a person to manage. Treat a commercial result as a research measurement with real error bars, not a verdict.
Educational reference material about the biology of ageing, cited throughout. It is not medical advice, it gives no dosing, protocol or clinical guidance, it is not tailored to anyone’s circumstances, and it makes no claim about any product sold on this site. Where an intervention such as rapamycin or metformin is discussed, that is a description of what the research examined.